3/29/2023 0 Comments Keylord guantes"Keloid and Hypertrophic Scars Are the Result of Chronic Inflammation in the Reticular Dermis." International Journal of Molecular Sciences 18 (2017): 606. "A Role for the E3 Ubiquitin Ligase NEDD4 in Keloid Pathogenesis." Journal of Investigative Dermatology 2018. "From Genetics to Epigenetics: New Insights Into Keloid Scarring." Cell Proliferation 2017 e12326 DOI: 10.1111/cpr.12326: 1-8. "Keloids and Hypertrophic Scars: Pathophysiology, Classification, and Treatment." Dermatol Surg 43 (2017): S3-S18. Radiation: Some doctors have reported the safe and effective use of radiation to treat keloids using a variety of techniques.Īndrews, Jonathan P., Marttala, Jaana, Macarak, Edward, Rosenbloom, Joel, Uitto, Jouni, "Keloids: The paradigm of skin fibrosis - Pathomechanismsand treatment." Matrix Biology (2016).īerman, Brian, Andrea Maderal, and Brian Raphael.Fluorouracil and bleomycin: Injections of these chemotherapeutic (anti- cancer) agents, alone or together with steroids, have been used for the treatment of keloids.Current research is underway using a variant of this method, applying topical imiquimod ( Aldara), which stimulates the body to produce interferon. In recent studies, injections of interferon have shown promise in reducing the size of keloids, though it's not yet certain whether that effect will be lasting. Interferon: Interferons are proteins produced by the body's immune systems that help fight off viruses, bacteria, and other challenges.Cryotherapy: Freezing keloids with liquid nitrogen may flatten them but often darkens or lightens the site of treatment.Pressure: Special earrings are available, which when used appropriately, can cause keloids on the earlobe to shrink significantly.Some doctors claim similar success with compression dressings made from materials other than silicone. Silicone gel or sheeting: This involves wearing a sheet of silicone gel on the affected area continuously for months, which is hard to sustain.These may be costly since such treatments are not generally covered by insurance plans. Treatment is safe and not very painful, but several treatment sessions may be needed. Laser: The pulsed-dye laser can be effective at flattening keloids and making them look less red.Superficial radiation treatment after surgical excision has also been found to be useful. Some surgeons achieve success by injecting steroids or applying compression (using a specialized pressure device where appropriate) to the wound site for months after cutting away the keloid. Surgery: This is risky because cutting a keloid can trigger the formation of a similar or even larger keloid.(These can be treated using a laser see below.) The keloid may look better after treatment than it looked to start with, but even the best results leave a mark that looks and feels quite different from the surrounding skin. Injections are usually given once every four to eight weeks into the keloids) and usually help flatten keloids however, steroid injections can also make the flattened keloid redder by stimulating the formation of more superficial blood vessels. Corticosteroid injections (intralesional steroids): These are safe but moderately painful.The nine possible procedures now available to treat keloids are as follows: What are nine treatment options for keloids? A keloid has a characteristic microscopic appearance and may be distinguished from a hypertrophic scar and a dermatofibroma.Other minor injuries that can trigger keloids are burns and cosmetic piercings. Keloids typically appear following surgery or injury, but they can also as a result of some minor inflammation, such as an acne pimple on the chest (even one that wasn't scratched or otherwise irritated). This tendency to migrate into surrounding areas that weren't injured originally distinguishes keloids from hypertrophic scars. Keloids, by contrast, may start sometime after a cutaneous injury and extend beyond the wound site. Dermatofibromas are almost never larger than ½ to ¾ of an inch and remain unchanged over many years.
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